MNF Week 16 Pick🏈

Tonight on Monday Night Football, the playoff-bound San Francisco 49ers (10-4) head to Indianapolis riding a four-game winning streak. Already locked into the postseason, a victory keeps their path open to claim the NFC's top seed and valuable home-field advantage throughout the playoffs. Meanwhile, the struggling Colts (8-6) face a critical must-win battle after dropping four straight, clinging to faint AFC playoff hopes that demand victories in all remaining games plus significant help from around the league. MNF, Let's Go!